The U.S. Department of Homeland Security (DHS) is committed to using and developing state-of-the-art technologies to make America safer. The DHS Science and Technology Directorate (S&T) is focused on developing innovative technology solutions and providing assessments, analyses and reports for the Homeland Security Enterprise. DHS's mission space includes preventing, detecting, responding to, and recovering from intentional or accidental introduction of biological and chemical agents that present a threat against the Nation's human population and critical infrastructure. The Chemical Biological Defense Division (CBD) within the Homeland Security Advanced Research Projects Agency (HSARPA) of DHS S&T supports this preparation for a biological threat event by identifying and developing technologies for DHS operational components to increase situational awareness, reduce potential consequences, and quicken appropriate responses. To ensure current and continuous customer, stakeholder, and developer feedback, DHS S&T is actively engaged with DHS operational components; federal, state, and local authorities; and industry to develop and transition new technologies that significantly improve upon current capabilities to respond to threats.